BASU LAB
Mechanisms that control DNA and RNA diversity in mammalian cells
DNA mutations and noncoding RNA expression can be both useful and detrimental to cells. Although somatically induced DNA alterations are important for B and T cell development, they are widely seen as drivers of various malignancies. Similarly, RNA expression both from coding and noncoding regions of the genome needs to be controlled by post transcriptional processing to prevent adverse effects including onset of RNA induced genomic instability, RNA interference, altered control of DNA regulatory elements, or activation of RNA induced inflammatory responses.
The department of Microbiology and Immunology
The Basu Lab is part of the Department of Microbiology & Immunology, in the Vagelos College of Physicians and Surgeons at Columbia University Irving Medical Center. We are members of the Graduate School of Arts and Sciences of Columbia University. Our Department offers a Graduate Training Program in Microbiology, Immunology and Infection.